A novel “chemical assembly line” that uses a ribbon made of polymer mesh that has sachet pockets containing a solid-phase resin that moves continuously through all the various chemical stages of manufacture.
The solvents, which react with the resin to produce the peptide, move in a counter current allowing for full utilization of the chemicals to minimize use of these toxic chemicals.
The optimization tool enables multifactorial process optimization – inc. varying multi process parameters such as: temperature, mixing power and assessing the impact on chemistry, purity, yield, durability –and can track end-to-end product quality.
Reduction in the use of toxic chemicals (such as solvents) by up to 100 times.
Dramatically reducing existing capital costs and making it possible to avoid building new multi-billion dollar manufacturing plants.
μLOT® modules are easily transportable anywhere and at any time due to their modular nature and smaller footprint, enabling multiple on-shore manufacturing operations that can be commissioned more rapidly.
The μLOT® technology enables adjustments to be made to the existing continuous manufacturing production line to accommodate different types of pharmaceuticals. No need to build a new plant.
Composite ribbon technology based on the functions of Houghten’s Tea bag (1985)